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1997-11-7 · A major characteristic of atherosclerosis is the accumulation of lipid-laden foam cells in the arterial wall. The foam cells are derived mainly from macrophages that have endocytosed modified lipoproteins through the scavenger receptor-mediated pathways ().The cytoplasmic lipid droplets are mostly cholesteryl esters, which exist in a dynamic equilibrium with unesterified …Deletion of Macrophage LDL Receptor–Related Protein ...2007-2-15 · First defined as a complex for removal of α 2-macroglobulin, 1,2 and then later identified as the low-density lipoprotein receptor (LDLR)-related protein (LRP), 3 LRP is a 600-kDa membrane receptor linked to numerous cellular functions and intracellular signaling events. 4 It has multiple extracellular ligands, including apolipoprotein E (apoE), lipoprotein lipase, …

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Town Surnames | JRI-Poland

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