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Autophagy and Aging

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Atlas of clinically distinct cell states and ecosystems ...

2021-9-30 · CE9-T cell states express activation and immunoregulatory genes, including markers of exhaustion, consistent with the association of CE9 with ICI response (e.g., LAG3 in CD8 T cell S3 and CTLA4 in CD4 T cell S1). In contrast, CE10-T cells express markers of naive and central memory cells (e.g., CCR7) ( Figure 6 A).Atlas of clinically distinct cell states and ecosystems ...2021-9-30 · (4) V i + ← {V i, i f V i > 0 0, o t h e r w i s e V i – ← {− V i, i f V i < 0 0, o t h e r w i s e V i ∗ ← (V i + V i –) To identify and quantitate cell states within V i ∗, EcoTyper applies NMF via Kullback-Leibler (KL) divergence minimization (Brunet et al., 2004), which starts with random initializations of the W and H ...

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Monaco Scott #2719 MNH Junior Chamber of Commerce …

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